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What is Simponi?

The generic name of Simponi is Golimumab Injection. Simponi is a prescription medicine and is used to treat the symptoms of Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, and Ulcerative Colitis. Simponi can be used in adults who have not responded adequately to other treatments and in patients who have not previously been treated with methotrexate whose disease is severe and progressive. It works by reducing the effects of a substance in the body that can cause inflammation that causes joint swelling and damage. At Buy Simponi Now you can easily Get Simponi by availing yourself of our online services. At Buy Simponi Now we have a wide range of original and genuine medicines to serve you in the best possible way.

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What is Simponi Used For?

Simponi is used for:

  • Rheumatoid arthritis and ankylosing spondylitis in adults
  • Psoriatic arthritis and polyarticular juvenile idiopathic arthritis in adults and children at least 2 years old
  • Ulcerative colitis (UC) in adults when other medicines have not worked

Simponi can also be given with Steroid Medicines to get and keep the UC under control and to improve the way the lining of your large intestine looks during colonoscopy.

How To Use Simponi?

Simponi is given by injection under the skin of the thigh, abdomen, or upper arm as directed by your doctor, usually once a month. Simponi is injected under the skin to reduce signs and Symptoms of Rheumatoid Arthritis, psoriatic arthritis, and ankylosing spondylitis, such as joint swelling, pain, fatigue, and length of morning stiffness. Carefully follow your doctor's directions for using this medication.

Why Simponi is Prescribed?

Simponi is a treatment for adults with moderate to severe rheumatoid arthritis, active psoriatic arthritis, or Active Ankylosing Spondylitis. Your doctor may have recommended Simponi not mentioned here. Always follow the instructions of your doctor. Do not give Simponi to anyone even if they have similar symptoms as you do.

What Conditions Does Simponi Treat?

Simponi is used to reduce pain and swelling due to certain types of arthritis such as rheumatoid, Psoriatic, and ankylosing spondylitis. By reducing joint swelling, the medication helps to reduce further joint damage and preserve joint function. Depending on the type, Simponi can be used alone or in combination with another drug called Methotrexate. Simponi is also used to treat a certain bowel condition.

Simponi Dosage

  • Usual Adult Dose for Ankylosing Spondylitis:
  • Initial dose: 50 mg subcutaneously once a month
  • Usual Adult Dose for Psoriatic Arthritis:
  • Initial dose: 50 mg subcutaneously once a month
  • Usual Adult Dose for Ulcerative Colitis:
  • Initial dose: 200 mg subcutaneously at week 0, followed by 100 mg at week 2.
  • Maintenance dose: 100 mg subcutaneously every 4 weeks.
  • Usual Adult Dose for Rheumatoid Arthritis:
  • Initial dose: 50 mg subcutaneously (SC) once a month or 2 mg per kg intravenous (IV) infusion over 30 minutes at weeks 0 and 4, then every 8 weeks thereafter

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Side Effects of Simponi:

Common side effects include but are not limited to:

  • Chills
  • Fever
  • Sore Throat
  • Mouth Sores
  • Lightheadedness
  • Cough
  • Shortness of Breath
  • Night Sweats
  • Loss of Appetite
  • Weight Loss
  • Tiredness
  • Skin Sores
  • Warmth
  • Redness
  • Diarrhea
  • Stomach Pain
  • Coughing Up Blood
  • Increased Urination
  • Burning Pain When Urinating
  • Skin Growths
  • Changes in Skin Appearance
  • Swelling of Your Ankles or Feet
  • Vision Changes
  • Numbness or Tingly Feeling
  • Weakness in Your Arms or Legs
  • Pale Skin
  • Easy Bruising or Bleeding
  • Right-sided Upper Stomach Pain
  • Loss of Appetite
  • Dark Urine
  • Clay-colored stools
  • Yellowing of The Skin or Eyes (Jaundice)
  • Muscle or Joint Pain
  • Skin Rash on Your Cheeks or Arms That Worsens in Sunlight, And
  • Red or Scaly Patches of Skin, Flaking or Pus
  • Infections
  • Cold or Flu Symptoms
  • Abnormal Liver Function Tests
  • High Blood Pressure
  • Rash, And
  • Pain, Itching, Redness, or Swelling Where The Medicine Was Injected

Cautions To Take Simponi:

  • You should not use Simponi if you are allergic to it or any of its ingredients
  • Simponi affects the immune system. You may get serious or fatal infections more easily
  • If you have ever had tuberculosis or hepatitis B, Simponi can cause these conditions to come back or get worse. 

To make sure Simponi is safe for you, tell your doctor if you ever had:

  • Active or chronic infections;
  • A nerve-muscle disease such as multiple sclerosis or Guillain-Barré syndrome;
  • Cancer or lymphoma;
  • Congestive heart failure;
  • Psoriasis; or
  • If you are scheduled to receive any vaccine
  • Tuberculosis 
  • Liver disorder 
  • Inform your doctor if you are pregnant or breastfeeding 
  • Inform your doctor about all the medication you may be using

Frequently Asked Questions

1. What should I avoid while using Simponi?

Do not receive a "live" vaccine while using Simponi. Avoid alcohol and smoking

2. Who cannot take Simponi?

Your doctor may not prescribe Simponi if:

  • you're pregnant or breastfeeding
  • you have HIV
  • you have multiple sclerosis (MS)
  • you've had cancer
  • you've had a heart condition
  • you have lung problems
3. What should I do if I forget a dose?

Inject the missed dose as soon as you remember it, and then inject your next dose at the regularly scheduled time. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not inject a double dose to make up for a missed one.

4. What are the pros and cons of Simponi?


  • Available in a prefilled syringe or autoinjector for easier use
  • Can be stored at room temperature for up to 30 days, if needed
  • Only needs to be injected once a month (except when starting it for UC)
  • Can be used for different autoimmune conditions


  • Only available as a brand medication so it might be expensive
  • Raises the risk of serious infections
  • Might be uncomfortable to use
  • Simponi prefilled syringe and autoinjector only used in adults

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